St. Pius X Parish is located in the most northern part of the city of Pueblo, west of I-25. Due to increased construction of multi-family and single family dwellings, the parish serves a growing population of families in all shapes and sizes. It is serving an increasingly more ethnically diverse population. The closeness of major hotel/motel construction in recent years has also increased out of state visitors during the summer.
The parish was established in 1954 to serve a congregation of approximately 300 families. Many of those families were originally members of Sacred Heart Cathedral, of which St. Pius was an offshoot. While the church was being built, parishioners either elected to attend mass at the Cathedral or they celebrated mass with Monsignor John Kelley at the VFW hall at 3200 Elizabeth. Msgr. Kelley was the founding pastor of St. Pius X.
Construction on the church began in the summer of 1955. The $300,000 original parish plant included a red brick church with four basement classrooms and an adjoining convent. By Christmas, the church was ready to celebrate its first mass. That summer on September 9, 1956, Bishop Joseph Willging dedicated the parish church named for Pope Pius X.